I have lived with this already a long time using Studio One 3, but now it is time to clarify this.
When pressing stop or operate transport related changes in any form, like jogging of rewind / fast forwarding, while Studio One 3 is playing, there is a high chance that you will hear an audible "click" sound (short audio spike).
It kind of bothers me a bit and this started from day 1. One also cannot say that it is very good for your monitors these HF spikes.
This is perhaps caused because it abruptly goes from a waveform to zero, although it is not really audible when starting playback. This would explain why playback is finished with it, or not when the waveform is on or near the center (no signal).
There must be something simple to do about it. Other DAW applications that I have experience with do not have this. Perhaps a short fade in/out through its outputs?
I use a RM32AI for playback.