I just purchased a 2018 Macbook Pro and at the same time updated my Studio One 2.6.5 Professional edition to the newest 4.5 edition. I have been spending the last 3.5 hours trying to figure out why in the heck I'm not receiving any signal from my Apollo interface to the Studio One inputs (an added aggravation as I've spent the last week going back and forth on Amazon trying to get the right FRIGGEN Thunderbolt 3 cable that isn't a charging one lol!!) The Console on the UAD software is giving me full signal recognition, and I've checked my routing over and over in the I/O menu in Studio One, and It's all correct. Studio One is definitely using the Apollo as the playback and recording device. I'm not sure if there have been any changes to the software that I have been out of the loop for since I bought the original software which most likely is the case, and I'm guessing that is where I'm getting tied up. I've been menu diving to try and find something that I missed, but I'm just coming up empty handed. In a last ditch effort I loaded up garage band (Because I didn't know where the fault in the signal chain was emanating from e.g. user error as most of my hardware is new at the moment, Apollo error, Mac error, or Studio One error.) Garage Band had no issue pulling the signal from the Apollo Interface so I'm really at a loss. I'm no novice in terms of technology as I build computers as a hobby. I didn't know if there was a bug in the newest software and considered going back to an older version of Studio One to see if that would fix the issue but that seems like a real hassle to go through. I was able to easily use the Apollo with my 2012 Macbook Pro and Studio One 2.6.5 edition so please send help! haha Thank You.