Presonus is really going to need to innovate in order to give its customers a usable, fast workflow for MIDI editing. The list above simply won't work. If clicking an existing note is allocated to selection, clicking an empty space needs to deselect -- it can't create a new note. If alt drag paints a series of notes then the current Copy command is lost. And what about velocity? That's one of the most important MIDI editing functions and it's not addressed at all. You have to get into multiple keyboard modifiers because everything else is taken. What a pain.
More importantly, even if Presonus were to somehow cleverly jam every conceivable MIDI editing function onto one smart tool, there's going to be a lot of unhappy users with kludged up workflows. For example, click drag up/down to create a note and set velocity (instead of pitch!) will never be a good workflow for a lot of users.
Presonus needs to look at creative solutions, in particular customizable tools. That way users can set up the MIDI smart tool to fit THEIR workflow, not a one-size-fits-all workflow dreamed up by someone at Presonus.
One other note: Please do NOT give us pixel-based note regions like in Sonar. That is a nightmare.