Sorry to hear about the recent issues you have been experiencing.
1. If you open the performance monitor in Studio One, you can view the resources that are being used by each of your plug-ins. See if you can find a particular plug-in or set of plug-ins that might be causing the issue. You may need to contact the developer/s of the plug-ins.
2. Make sure you have the most current driver for your audio interface.
3. Please check your hard drive speed. If you are running a 5400 rpm hard drive as your system drive. You will want to replace that hard drive with a 7200 rpm hard drive or higher. 5400 rpm hard drives are too slow to edit and record audio.
Please go into Studio One > Preferences > Advanced > Services and disable your ARA, AU, VST, VST3, and ReWire services. See if you can find a correlation to the issue and a particular service.
With all the services disabled:
1. Enable a service, and test if the issue remains
2. Enable another service and test if the issue remains
3. Keep doing this until you find which service the issue lies in
Then you can narrow down where the culprit plug-in is. You may need to contact the developer/s of the plug-ins should you find one to be the cause of the issue.