Well, given the added DSP chip UAD are using, a bit of this kinda sorta already exists in StudioLive series. They have FatChannel plugins running natively on the mixer. Plus, it's not just a mixing desk, it's also an audio interface. So, yeah.
Now, it doesn't run all Studio One plugins from there. And it doesn't really off-load all the Studio One compliant plugins to a peripheral CPU. So, it's not a 1:1 thing. But, it's kinda close.
I will say this, though: If PreSonus were to approach this issue at all, I'd like it if they delivered a PCI connected daughter card (ideally PCI 4, for speed/latency gains) for distributed computing on some kind of open DSP standard. But, this is bigger chore than it sounds like and it's hardly a solution on it's own. Quality of design at a motherboard level is an issue across the computing spectrum. And that matters as there is a controller chip involved with PCI lanes; I'm simply preferring it because of superior throughput speed and it has the fewest potential points of failure before factoring devices you would attach. In service to this idea, I'd suppose this is where a multi-core FPGA would come in super handy. Let it reprogram itself for processing jobs relatively on demand. Audio DSP might be somewhat redundant, but not by that much; plus, it allows for adaptability to future DSP instructions/standards.
I've side-tracked myself a fair bit here. It all boils down to the fact that your suggestion is tricky, it's expensive, and ─ no matter how much I love Studio One ─ I'm not sure they've quite hit market share big enough to make it worth their effort. But, if they start planning for it as a what-if, the day it's worth the effort, they could have the platform code more prepared. Always build for the future.