Possible, yes, is there a better possibility, yes. The thing about inter connection is impedance, voltage, instrument/vocal...all play a part in the performance of the system, and ultimately the sound quality.
It's not like it can't be done, but unless you have the proper interface to "Properly" connect the devices, there WILL be sound degradation. You CAN hook up without damage, but only you can determine if the setup 'sound's right or not.
Low impedance instruments like guitars, don't sound right (in my opinion) plugged into the
line level input. The impedance of an input channel is upwards of 50K ohms.
Then you re-amplify the already imperfect signal.
Pay attention to input and output specs of the devices, and use interfaces for proper signal transfer and you might get that perfect performance, or recording... otherwise, you will undoubtedly second guess your mix...
