Please check out these two guides, which will assist you in setting up your AudioBox:
1. This guide covers common AudioBox setup and configuration issues, as well as addresses basic reasons for the device to not seem to function properly:
http://support.presonus.com/entries/21351334-why-won-t-my-audiobox-record-or-play-back-audio
2. If the above guide does not resolve your issue, the driver may need to be uninstalled and reinstalled properly. Below are instructions for how to do this:
Windows Vista and Windows 7:
http://support.presonus.com/entries/21524610-how-do-i-uninstall-and-reinstall-my-audiobox-drivers-in-windows-7
Windows 8, 8.1 and Windows 10:
http://support.presonus.com/entries/21469744-How-do-I-uninstall-and-reinstall-my-AudioBox-drivers-in-Windows-8-or-Windows-10-
If you're still having issues, please create a system profile for me using the instructions in the articles above and attach it as a reply. I will then be able to examine your system and provide you with further troubleshooting.