Studio One (on Windows) currently follows OS scaling factor which is nice, but most other DAWs - Bitwig, Live, Cubase, even Reason now - allow to set separate scaling for DAW itself, so e.g. I can run Windows at 125%, but DAW is at 100%. That's not possible in Studio One currently. One can disable high-DPI support and set Windows compatibility options to not scale Studio One automatically, but then many plugins have problem and user can't anymore decide if they should be scaled or not - in practice this "workaround" makes it unusable.