Here is the response from presonus that worked
The issue here is that you are running Universal Control 2.0 which is not compatible with the StudioLive 16.4.2.
In order to use both the StudioLive and Studio 192 on the same computer your will need to uninstall Universal Control and reinstall in a specific order.
Please download Universal Control 2.0 here:
https://pae-web.presonusmusic.com/downloads/products/dmg/PreSonus_Universal_Control-41902.dmg
**Please run the uninstall package first then reinstall Universal Control 2.0.
After installing UC 2.0 please download UC 1.7.4 here:
https://pae-web.presonusmusic.com/downloads/products/dmg/PreSonus_Universal_Control-174.dmg
You will need to use UC 2.0 for the Studio 192 and UC 1.7.4 for the StudioLive.