For a 4.5" speaker, I recommend pairing them with a subwoofer. Me personally, I wouldn't go below a 6" speaker without a sub.
Remember, these recommendations are just that. At the end, you use what you have for resources. More important than all these numbers, is knowing your gear. I have mixed projects on earbud, and home stereo equipment. If you know your system, and listen via other sources, you'll be fine.