Hi,
can you please provide a bit more information about all the different software you're using?
Which OS, 32/64 bits? Which edition of Studio One? Prime/Artist/Professional? Which version of Studio One? 32/64 bits? Which version of the Arturia Prophet V? 32/64 bits? VST2/VST3?
What I can tell you is that on Windows 7 64 bits, with Studio One version 3.5.0 64 bits, I can use Arturia's plug-ins, such as the Prophet V3 from Arturia's Collection V, and it's working just fine in both VST2 and VST3 formats (64 bits of course).
I did have a period of time where Arturia's plugins were acting up. It was right after an update to Studio One (3.4 I think), where none of the Collection V plugins would even display their GUI. After much searching, it was actually my video driver that needed to be updated. The darn thing was that Dell didn't have any later driver as my laptop is becoming quite old now. I simply went directly to the video card vendor's website to download the latest driver, and voilĂ !
So, please provide a bit more details about your specific setup, and in the meantime, please make sure all your drivers are up to date.