If you are using a DAW other than Studio One, then make sure Mixer Bypass is enabled in the settings page, then assign your outputs the way you would like in your DAW.
If you are using Studio 192 stand alone with just UC Surface, then you have to setup Mix Bus settings to decide which input routes to which output depending on which Mix Bus you have selected.
Please review section 4.2 (page 42) of the User Guide for Studio 192 and UC Surface to learn more.