Question

I installed Studio One Artist 2 on a MacBook. When I open one of the installed demo sessions, I can see that the song is playing, but I am not getting any sound over the computer speaker. The computer is not connected to the mixer board. I have confirmed that the audio is working on the computer.

Answer 1

If you are playing audio through USB speakers connected to your system set Preferences > Audio Setup > Audio Device  audio device tab "Playback Device" to those speakers.   They should show up there to chose directly.

If your speakers are connected otherwise like to a headphone output via 1/8th inch cable, choose "Built In Audio" in that screen.