The two most common reasons that this can happen are the location of your User Data folder or the driver for your audio interface. By default, Studio One saves to Documents>Studio One>Songs. If you are backing that folder up using iCloud Drive, that could be the issue in that the folder is not accessible. Here is a link that explains how to reverse this.
If you are writing to an external drive, make sure that it is not set to "Read Only." Make sure that you have permissions to write to the drive.
As for the driver for the audio interface, try using "built-in audio" just to test with and see if the issue persists.
In looking at your account, it appears that you have an active ticket open with us. Please continue to troubleshoot there.