This issue should be resolved in Studio One 4 build 4.6.1. Please update. If you receive an error regarding permissions after updating, please follow the instructions in the article below from the PreSonus Knowledge Base.
https://support.presonus.com/hc/en-us/articles/360038725572-Permissions-error-message-on-some-Macs-that-prevents-the-installation-of-Extensions