Hello, I wrote the details in this forum post
https://forums.presonus.com/viewtopic.php?f=151&t=42895
The long story short is in Studio One 5, recording/playback/transport only works with ASIO4ALL which has extremely high latency but not my native zoom uac-2 drivers.
In my installation of Studio One 3, the zoom uac-2 works perfectly. Every other audio app I have also works perfectly with my ZOOM UAC-2.
I don't really need the new features, can I please just get a refund?