I get sound when I score or write notes, when I move them around with arrow keys, etc.
Did you download and install the bunded sounds?( Woodwinds, Strings, Brass, ect. that are listed at the bottom of the Notion Page in your my.presonus account > Product > Notion 6 > Just below the installer for Notion.)
Have you checked in File > preferences to make sure all the boxes with echo listed are checked (Echo note entry, Echo selection, Echo midi input), since that's the settings that do that. If they are checked, does it play audio at all? If not, double check to make sure you have loaded a synth on the track (on windows, click on a staff and hit Ctrl+i to view the instrument on that line or click the name on the top of the mixer), if nothing pops up you don't have an instrument loaded and you need to set one up. You do that in Score Settings, click on the gear next to the track, it's under instrument. If you don't have any instruments you need to add your 3rd party VSTs through File > Plugin Manager and verify the location for Notion's Bundled Sounds are set at the right location File > Preferences > Audio Tab > And select the location of your sample folder.