You can use your regular QWERTY computer keyboard as a MIDI Keyboard to play virtual instruments and record musical data in Studio One. To do this, add a new device in the Studio One/Options/External Devices/Add Device menu (Mac OS X: Preferences/External Devices/ Add Device), choosing the QWERTY Keyboard device from the PreSonus device folder.
With the device added, to use your keyboard as a MIDI Keyboard, open the interface for the QWERTY Keyboard device by double-clicking on it in the External panel of the Console. Any record-enabled Instrument Track then receives input from the QWERTY Keyboard, as shown in the QWERTY Keyboard device interface. Your keyboard only transmits data to Instrument Tracks while the QWERTY Keyboard device interface is open.