Currently, what we get are small fonts, and often difficult to read colours: Grey Text on a Black background, and those are the positive points !
I feel that Bitwig Studio has the best and most accessable GUI of them all. Yes, that too has a very dark background. But what you get with text is in complete contrast: a brilliant white. And the size of text on my IIyama HD screen is makes working a pleasure !
People with vision impairment still need to get their work done - but Studio One currently makes life very difficult for those of us with less the good eyesight. Studio One is not the only culprit of course; Cubase leaves much to be desired - so too Steinberg's instrument plugins.
Give me the option of a Bitwig-style interface, and I will very happy.