Sorry to hear about the recent issues you have been experiencing.
If you have the drivers for that device installed and they are not meshing with Studio One, you can go to the OS X Audio MIDI setup and create what's called an Aggregate Device for that particular interface: https://support.apple.com/en-us/HT202000
Then select this Aggregate in Studio One > Preferences > Audio Setup. Then try to assign the I/O again.
If that does not work, please create a support ticket to discuss this in more detail.
Here is a link to create a ticket: http://support.presonus.com/hc/en-us/requests/new