You will want to make sure that you have the 64-bit version of Studio One 3 OEM installed. You will also want to make sure that you have the 64-bit version of Piapro installed. Studio One 3 Artist OEM will scan your c:\Program Files\VSTplugins folder. You may want to try re-installing Piapro and verify that you are installing the program to your Program Files folder and that you are installing the VST to the VSTplugins folder. If you are doing everything correctly, try removing your settings files from Studio One and see if it will re-scan.
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Go to Help>Open Settings folder.
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Copy the contents of the folder over to a folder on your desktop.
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Close S1 and delete the contents of the settings folder with the exception of the user.license file as well as the "Extensions" folder.
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Open S1 and go to Studio One>Options (Preferences on a Mac) to reconfigure your settings.
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Test to see if the problem is resolved. If it is not, please feel free to copy your settings files back over from the backup that you created in step 2.
*If you are missing presets or Sound Sets after doing this, simply double-click one of your Sound Sets under Documents>Studio One>Sound Sets.