I am an old schooler, who began experimenting with digital audio composing on twin Amiga 2000s, back in 1987, using 5.25 floppy disks and 'Personal Composer, Version 1.0' and Blue Ribbon Soundworks 'Pipes & Bars' software, that were the best tools of the day, but now a joke by today's DAW standards. I have built a number of computers over the years, and have just enough knowledge to be dangerous.
I'm not a big fan of relying upon one USB-C cable - to handle audio system requirements within the studio. For those wanting something quick and slick, to handle their portable requirements - I get it.. There is lots of good info out there on this choice and topic.
For me, the more connectivity options, the better. Not knowing exactly what audio devices I will be buying into in the future, I want to ensure that I have all the bases covered. So, onboard TB3, and USB 3.1 Gen 2, Type C, along with many other quality features available on the following two (2) motherboard EXAMPLES, are in my opinion, two very worthy contenders for a powerful (future/contemporary and backward compatible) audio and video management system...
Here is one of the better lists, I've found online recently, that although not endorsed by Presonus, mentions a number of computers that may work for you, depending upon your system needs... I don't think, given today's standards, there is any one generic (BEST) solution out there in the industry. Everyone has an opinion on this subject, but I recommend that you do your own research, before making such an important investment. If you fully understand TB3 and USB-C protocols, you are miles ahead of me. At the end of the following article, I found some of the reader comments about single vs multi-port TB3 options, interesting to say the least and something requiring serious thought, should you be going the TB3 route. Checkout the following link for more info.
I suspect in the next couple of years, gear much like Steinburg's new AXR4 AI featuring TB2 (Thunderbolt 2) and 32bit/384 kHz sampling, will be the new standard. I am hopeful that Presonus and others in the industry will be adding TB3 & USB 3.1 Gen 2 Type C ports to all future hardware, in order to rocket beyond older TB2 & (USB 2.0 technology, which apparently and confusingly is still being utilized by manufacturers) behind a modern USB-C port.
In closing, it is my opinion, the more: computer power (i7 c/w a better than average number of lanes, to better handle multi-device internal processing); RAM (Fast); Storage: Fast, Conventional and Fail Safe Backup Solutions), that you have on board, in concert with all of the other computer related goodies, one typically needs to best manage the quality video output(s) and (ideally) your near latency free audio dataflow, the less headaches you should have in the future, when adding newer and more demanding audio hardware into your setup :)
There are many good folks out there, who know much more about this stuff than me. This is just my (old) two bits worth.
I hope this is helpful. Good luck.