not sure to be honest. since mojave 10.14.3 and also now with 10.14.4 i had those crackling/noise issues. i also made a factory reset on the 1810, tried with the old firmware and after again with the current 1810 firmware. still no improvement. i even installed the old ableton 10.0.5 (where it was working before) no improvement. BUT i'm now down to that point, that ableton probably is the problem. hoping for a change in ableton 10.1 - if they finally are going to release it! --> in studio one 4 i didn't had those issues during my recordings.
the main problem was the mojave update, cause ableton 10.0.5 and 10.0.6 is not compatible with mojave 10.14.3 and 10.14.4.
the presonus 1810 or it's firmware doesn't seem to be the problem in that chain here.
related to your comment: i never had problems with listening to music via the presonus studio on youtube/spotify or whatever. my problems are only when i'm using the inputs of the interface (recording). in your case it really sounds like your windows/mac os is not compatible with the firmware of your interface. i had exactly the same problems like you discribe a few years ago with my steinberg ur44 or ur22 mk2 and it was because of the firmware of the steinberg. maybe presonus will release a new firmware soon.
hope that could help you.