Studiolive 24 series 3, 24R, 4 earmix, presonus AVB router, studio one pro 4. Mac Pro OS 10.12, lots O'Ram
Updated firmware on all hardware, UC surface and studio One to latest versions right off the bat started getting all sorts of clicking, popping and hissing on multiple channels of studio one. Sounds a lot like a clocking sync issue. But even after disconnecting all hardware several reboots, would still get it with just the mixer hooked up via USB.
Finally decided to swap out computer with another Mac Pro OS 10.12 got rid of the popping etc. but ran into lots of odd issues with DAW mode. When switch to a mix send or fax send with console hitting the main mix button wouldn't light or do anything. The only way to get back to main faders was by hitting th fx or mix button to turn it off. Main mix button would not work. Weird issues with setting gain while using the 24r in stagebox mode. AVB sends to earmix systems was all out of wack even after double checking AVB routing and digital patching. Got through an hour long overdub session by using main mix foer headphones. No talkback and trying to deal with DAW mode control issues. After the session I stayed late and ended up going back to original computer rolling back studio One 4 to pre flex update, UC surface to pre flex update and going back to pre update firmware on mixer and 24r stage box..... thankful everything is back to working and I can get back to my busy week of sessions. This update really killed me, going to wait for a bit and keep checking posts until I feel confident to try again. So much for the presonus eco system being as stable as most of the previous products. I've been a strong presonus user and promoter and have faith in presonus getting this right but be cautious with this update and leave lots of time to test.... don't forget to backup your mixer if you have lots of scenes. That was my saving grace