Midi controllers generate no sound at the device. I use the Studio 192 as my audio unit but I use many midi over usb devices, including but not limited to the Atom and the Atom SQ, Roland A-800 etc. The midi performance information is passed via USB on all devices, all are recognised by S1. All sounds are then sent thru, from Studio One to the audio device (192). So, in theory, your "midi to usb" connector should be seen as a standard midi controller.