Have you tried one of your other 4 activations you have? You should start a tech service ticket. I would also suggest uninstalling S1 and reinstalling from your account. The Knowledge base:
http://support.presonus.com/forums
has all the information and instructions to perform the task.
Please, if you want a more detailed answer you need to include the information requested above the question field where you as the question... it
s in BOLD RED print... Info like WHAT computer >processor > ram > interfaces > was that the boot drive that went bad... do you have more than one drive (storage) ETC...