Mac OS X is structured by Apple to only be compatible with authorized Mac hardware. Since the Mac OS is tailored specifically to the type of hardware contained in native Macs, it is not prepared to run on completely third-party systems, which are alien to the OS.
While sometimes Mac-on-PC computers may operate fine, there is no way to confirm the stability of the operating system due to the wide array of PC hardware available and the unlicensed hardware drivers that are needed to make it all possible . Therefore, PreSonus does not officially support the Mac operating system unless it is installed on native Mac hardware from Apple.