You are better off running any recording software offline with antivirus programs turned off. Yes they can affect you in a number of ways.
They can slow down your processes, interfere with your installations, and even corrupt your installations. If you have 2 computers, use one for strictly recording. If not, set up a new user labeled recording and install all of your music software there, keeping your internet and antivirus switched off except when downloading updates and new software. Remember to download only from companies that you're familiar with.