Apple have made changes in how our drivers are installed. Please see the following for installation Issues with FireStudio Series on High Sierra Mac OSX 10.13
Link: https://support.presonus.com/hc/en-us/articles/115005456483-Installation-Issues-with-FireStudio-Series-on-High-Sierra-Mac-OSX-10-13
Please note that the warning on the first screen shot may not show unless you uninstall and reinstall Universal Control. You will only have 30mins from the time you install Universal Control to give the exception required to install.