Yes. SPDIF Output 5/6 is another assignable output in your DAW, just that it is hardwired to the RCA Coax SPDIF Jack on the back of the unit coming from the pigtail. You'll need a D/A SPDIF converter or studio monitors with a SPDIF Input to decode the signal to analog audio.
The Studio 6|8 get's it's name from the number of I/O:
- For the 6 inputs, 4 analog, 1/2, 3/4, SPDIF 5/6
- For the 8 outputs, 4 analog, Main L/R, Line Out 3/4, SPDIF 5/6, Headphone 7/8