Greetings. My studiolive series III 24R, which I use almost exclusively as an audio interface, always crackles when playing back from Cubase, no matter what my buffer settings are:
ASIO meter shows no processor spikes at all, and overall processing is always fairly low. Direct monitoring is flawless, and wave files are recorded without any problems. The problem is exclusive to playback, with one or whatever number of tracks.
I'm using a fast ASUS N751JX with Intel® Core™ i7 4720HQ processor, 16GB RAM, SSD drive for system and programs. Windows 10 and Cubase.
I've owned a few different audio interfaces with this same system and setup, wich I already have optimized for audio work, and this is the only one that does this.