My Studio 1810c is plugged into my Mac Mini via a fresh and high-end USB-C cable. I'm running OS 10.15 and the newest version of Universal Control 3.4. It's running out via coaxial to my amplifier.
If I play music, say via iTunes, it'll work for a few seconds. Then the sound will stop, the level lights on the 1810c will drop. iTunes continues to play.