In my opinion your GPU is overkill for music work. You should be able to handle 4+ monitors with a GTX 1060 6GB with no worry to resolution. I would guess it's an update to the VSTi inside Studio One not playing with an old update VST plugin or something.
If I recall, Studio One (5.2) just got "hardware acceleration", you could disable that to see if it works better. Also updating your Nvidia drivers could help if you haven't updated in sometime.