In the image below you'll see that i've crudely edited the plugin GUI header to include the Activate and Bypass buttons next to each plugin that is in use on a track. In the example you'll see next to the Delay, Chorus and Mixverb dedicated activate/bypass buttons.
Why is this useful? Well it allows the user to bypass/deactivate a plugin without having to select and open the plugin. With any plugin's GUI open you can bypass/activate any other plugin from the GUI header. This would mean making each plugin instance a little bit longer to accomodate the additional buttons but i believe workflow will be improved as a result.