Question

I have to unplug and replug my AudioBox iOne to get it work on my iMac. 

Each time I turn on my mac I have no sound. I then need to disconnect and reconnect the interface in order for it to work. Is this normal behavior? 

Audiobox iOne

• Driver version: 1.81.0.5653
• AudioBox VSL 1.3.5653
• Firmware ver 1.25

Computer

• Model Name:    iMac
• Model Identifier:    iMac16,2
• Processor Name:    Intel Core i7
• Processor Speed:    3.3 GHz
• Number of Processors:    1
• Total Number of Cores:    4
• L2 Cache (per Core):    256 KB
• L3 Cache:    6 MB
• Memory:    16 GB
• Boot ROM Version:    IM162.0206.B00
• SMC Version (system):    2.32f20

Answer 1

We need more information to assist here.

What is the context in which you have to disconnect and reconnect it?

Is your computer going in to sleep mode at any point?

PreSonus hardware isn't supported with sleep mode enabled and will almost always require the device be resynced for use.

If the computer is not going to sleep at any point, please try connecting to different USB ports. This can fix any number of issues.