Yeah, I had the exact same issue. Was driving me insane!!! But, I was able to fix it by going onto my Presonus page, expanding the view under My Products (Studio One 3), then scrolling down to Extra Downloads. There, you should see a free Melodyne trial. Download the zip file, but SAVE it to your computer (won't work if you just open it). Once it's saved, find the SETUP folder within the zip file, click on it, then follow the instructions. THEN, go back to your Presonus page, and click on the Studio One 3 installer for your system. Once I did all of this, I could get Studio One to function, and all of my presets were fine. Presonus is aware of this, so hopefully a patch will get here soon. Lots of people are having the exact same issue. Hope this helps!