Hi,
1. Make sure you have the latest version of Melodyne installed. If you still experience issues uninstall it and install it again. If that doesn't help try refreshing Studio One's application settings as described below ...
1. Go to Help>Open Settings folder.
2. Copy the contents of the folder over to a folder on your desktop.
3. Close S1 and delete the contents of the settings folder with the exception of the user.license file as well as the "Extensions" folder.
4. Open S1 and go to Studio One>Options (Preferences on a Mac) to reconfigure your settings.
5. Test to see if the problem is resolved. If it is not, please feel free to copy your settings files back over from the backup that you created in step 2.
*If you are missing presets or Sound Sets after doing this, simply double-click one of your Sound Sets under Documents>Studio One>Sound Sets.
2. This is a known issue in 3.5.1 that will be corrected in the next maintenance update.