These articles should prove useful for you.
http://answers.presonus.com/854/can-use-macbook-air-with-the-studio-one-and-presonus-products
http://support.presonus.com/hc/en-us/articles/213882323-Mac-OS-X-10-12-macOS12-PreSonus-Compatibility-Statement
If you are experiencing issues with any PreSonus hardware or software once you've updated to Sierra, please contact tech support via your user account at my.presonus.com and we will be happy to assist you.