I have the same issue with Faderport and CUBASE 5 windows 10 64 bit
Ive spent a couple of days now installing and uninstalling this driver, ive used the latest one from the presonus website that the Admin suggsted here and have had no luck. The installer goes through install but the presonus isnt listed in Devices as it should be.
I know I can Use MACKIE controll but im limiting myself to what this unit can do. Waste of money, and I wont be buying a Presonus product again for the Lack of customer support this company has.