Thank you for contacting Presonus Technical Support. Sorry to hear about the recent issues you have been experiencing.
1. Do you hear the noise in headphones and speakers? Please try with only the headphones connected.
2. If there is no noise when only the headphones are used, try using balanced cables between the audio interface interface and your monitors.
Here are some additional troubleshooting suggestions.
1. Make sure power conditioners, power outlets are properly wired, polarized and also grounded.
2. Isolate power for devices .
3. Isolate power to speakers away from computer.
4. Isolate power to hub away from computer and or speakers.
You are also encouraged to submit a support ticket if none of the above helps. Here is a link to create a ticket: http://support.presonus.com/hc/en-us/requests/new