I have found the solution for this...
I bought one of these units too, as their equipment is generally considered decent, it looked good and had good reviews. But immediately I was getting cracking and popping all the time, even when audio was not clipping. I tried all kinds of different things for a few weeks and then finally came up with a solution...
Put it back in the box, give it to a friend and tell them if they keep the master output in their audio application about 80% it works most of the time. Then buy a ********* UMC 202HD. It's the same price, supports 192 kHz and has absolutely no faults. You can even play audio at a couple DB above clipping and it's completely content. For all the belittling that ********* equipment gets, I've owned multiple pieces of their gear through the years and every one of them has performed as good or better than other pieces of similar gear at a lot less money.
Alternate solution: you can just throw the Presonus in the trash, as that's about what it's worth.
EDIT: That's hilarious, they won't let me use the name of a competing company, they put little stars. What a sad company. Won't ever buy or use any equipment or software from them again.