I'm a Studio One 3 Pro user, but I've been reading about Cubase's Control Room, and I believe it's a feature many many many Studio One users would really appreciate.
The premise behind the feature is software control for monitoring. It provides a set of options for selecting monitors, creating cue mixes, and managing how it's all used. Studio One can definitely benefit from a similar feature set.
Let's imagine I have an interface--any interface--that gives me four pairs of analog outputs and four pairs of digital outputs, plus some number of inputs for recording or external sound sources (iPhone, artist's laptop, etc.). I have two pairs of monitors, and a headphone amp at the mixing desk. I connect the monitors/amps to my first two pairs of outputs, I leave one pair open for things like re-amping, and I connect the final pair to my headphone amp. I also use ADAT to connect the four digital pairs to a DAC I'll use to feed headphone amps in my live room.
Now, I need some way to control all of that from the computer, since my DAW is my console.
First, there would need to be a way to tell S1 what outputs are what. So in the Audio I/O Setup grids, you could specify that certain inputs and outputs are Aux In 1, Aux In 2, or Monitor A, B, C, or D, or Cue Outputs, or Headphones. That way the outputs are well defined and can be dedicated to their intended purposes. If you needed to route a channel directly to the monitors, instead of going through the Main Bus, you could route it to "Monitors" as opposed to "Main". And speaking of...
In S1, there could be a panel the size of the Record panel below the edit, mix, or arrange views, in which you can easily fit controls for monitor switching (A, B, C, etc.), monitor source selection (Main, Aux 1, Aux 2, etc.), and monitoring level that's separate from the main fader. Next to that, buttons for dim (and its level), mute, mono, side image solo, channel swap, and even "dim solo"/"listen" mode toggling. In addition, a Talkback section, and a headphones section with its own level that uses many of the same options as the monitors.
Then, as maybe a separate channel type in the console's Outputs view, there could be options on the appropriate outputs for the Cue mixes for things like PFL/AFL and Click send level, while in the main console view, Cue sends are distinguished from normal PFL/AFL sends better than just being permanently visible above the channel I/O. A pop-up menu below/next to the Track List could let you select a Cue mix for Sends On Fader. Output faders could act as output trims. And of course, what makes Cubase's Control Room so cool:
On all the outputs, an insert rack for plugins! So EQ and limiting could be on the Cue mixes, while each of my sets of monitors could have their own instances of Sonarworks Reference loaded up, and I wouldn't need to worry about bypassing them all before exporting a mix.
There's lots of engineers using digital mixing consoles as their studio interfaces. Sure, they have similar-ish routing available within, but without mapping every channel's output in the DAW to a fader on the mixer, you don't get quite the cue mix capability from the hardware you do from the software. Having these options in the box would make even AudioBox VSL-sized setups complete, 100% solutions for a recording/mixing studio. Kind of what comes to mind when I hear "Studio One."
I think this feature set would go a whole lot further than the features in VSL did, especially with Native Zero Latency Monitoring technology in S1.