Question

The recording line is set to Presonus and the playback is set to the speakers.  No sounds comes from the speakers.  I do have Studio One working and it shows receiving signal.  Playback through headphones.  Not speakers.  If I can't playback through speakers, I don't need this device.

Answer 1

You can not use onboard audio at the same time as an audio interface like the itwo. To use the pc speakers, you need to go in to options, and under audio setup, where it lists the itwo, select Windows audio. Then you will need to switch back in the same process when you want to record and use the headphones.