Let's start tracking who is having problems with preamp gains resetting to zero.
Please make sure you include which mixer you are using, what inputs are being affected (AVB or Analog), and what you are using for a stagebox (NSB or 32R, etc.) if applicable.
This seems to be associated with the power up sequence between stageboxes and mixer. But, I have seen a few people on Facebook mention it is happening on analog inputs as well.
I am using the SLIII 16 with NSB 16.8 and occasionally on power up some of the inputs from the NSB are at 0 and it doesn't matter if you recall a scene where the input gain was definitely set to something else. I have also had problems with 48V being turned off at random times, I am 100% sure that this is related.
The more people who report accurate accounts of what they have experienced the better. I hope this helps Presonus track down why this happens and a way to fix it.
Let's be respectful, provide great info for Presonus and make sure you UP VOTE!!!