Every time you need to change modes you 1. power down the unit. 2. press next(redo) and power on the unit at the same time. 3. once all the unit lights flash on/off; select which DAW you want to control from the top two rows (not the bottom mute, that is only for speaker muting only!) SOLO,-for Studio One, MUTE-LOGIC PRO, BYPASS-PRO TOOLS, ... ETC. Refer to the PDF Manual for the other Mode Changes, those are the ones I remembered off the top of my head. I hope that helps.