Hi. I'm just giving my experience with this issue, in case it could be useful to some other presonus user...
I'm also seeing that most questions are a little older and or not solved.
The issue: crackling while playback (on any DAW soft or windows sounds)
2023-nov-08
Laptop Acer Nitro 16 (AN16-51). i7-13700H, 16GB RAM DDR5, 1 TB NVME, NVIDIA RTX 4050 laptop GPU / Windows 11 23H2
Presonus StudioLive Series III 24 & 24R (both)
My laptop is brandnew. Presonus equipment were older and in use with others PC flawlessly
Obviously my problem was with my new laptop (is a nice laptop, so there had to be "something" to do)
I tried several settings with mixers (44.1/48 - 16bit/24bit - buffer size - compatibility mode - updates). > Nothing
Then tried other optimizations at the laptop. Almost everything (except some functions that couldn't be -dropbox, drive, etc.-) > Nothing
BUT WHAT WORKED for me, was going to: System properties > advanced system settings > Performance Settings > Advanced > Adjust best performance for background Services.
After this, no more crackling while playback.
Hope this could help any one before loosing too much time!