A lot of plug-ins are still running old code, this will cause high CPU usage and the crashing you're seeing. Make sure you have latest versions of the plug-ins that you're using when your system crashes.
Make sure your system is up to date as well. Studio One 5 is using latest Visual C++ Libraries, your Windows 10 system should be version 1709 or later. To tell which version of Windows 10 you have go to the search in the taskbar and type: winver.