I found this solution on the NI forum and it seems to be working.
Reset Kontakt's database information to its default library and user paths by the following:For PC go to C:\Users\*username*\AppData\Local\Native Instruments\Kontakt 5
Some folders may be hidden. So, to enable hidden folders on PC if you don't know how, read this:
For Mac go to Macintosh HD > Users > ~ > Library > Application Support > Native
Instruments > Kontakt 5 > Db
Note: On newer Mac OS computers where 10.7 or a later version is installed, the
User Library folder is hidden. To access it, click on the Apple task bar entry
named Go and press down the Alt key. The Library entry will become visible in the
drop-down menu and can now be selected.
Locate and Delete the Factory.kdb.cache, kontaktdb2 and kontaktdb2lock files
Empty Trash/Recycling Bin
Then restart Kontakt. This rescan will take a few minutes.
Like I said, this seems to have corrected all of the issues that I was having with Kontakt and Komplete 10 in general when used as plug-ins in studio one.
Best of luck!