I have a simillar problem, it only works on one of my usb 3 ports, which is a bummer.
I have an AMD ryzen 7 2700x and a rog Crosshair VII hero motherboard.
Apparently Presonus couldn't be less bothered since this post dates from feburary... no response.
It took them 4 days to moderate one of my answers, so I'm not that surprised.
I won't be buying any of their products in the future.