The latest firmware update was November 19, 2019 and it didn't change anything basic, so I suppose it's more a communication problem between mixer and computer. It's the audio interface which tells Studio One to run in sample rate A (44.1 kHz) or B (48 kHz) and you should NEVER toggle between sample rates. Never! Start the mixer, select the sample rate, then start Studio One (or Capture). This should work without any problems.